research

I am currently teaching at San José State University in San José, California in the Biomedical, Chemical, and Materials Engineering Department. Over the course of the next couple years, I will be developing a set of core competencies in the Biomedical Engineering Laboratory centered around growth and characterization of clinically relevant bacterial biofilms. The goal of my work is to investigate the interplay between bacterial biofilms, specifically those produced by the bacteria Mycobacterium smegmatis, and lung tissue. Additional work will investigate novel dielectrophoretic techniques for size-independent particle sorting. 

See research page for more active projects and openings.

Previously, I was working as a National Research Council (NRC) Postdoctoral Fellow at the National Institute of Standards and Technology (NIST), Biochemical Sciences Division. My work focused primarily on microfluidic techniques for cell manipulation and characterization. Previously, as a graduate student in the Micro-/Nano-fluidics Laboratory at Cornell, I worked to develop insulator-based and electrode-based dielectrophoresis techniques for cell manipulation and characterization, respectively. The results of this work include the demonstration of novel, size-based separation of multi-component suspensions in high-aspect ratio, polymeric microfluidic devices and the characterization of mycobacterial subpopulations based on membrane phenotype. At NIST, I engaged in two primary research efforts: (i) development of microfluidic techniques for growing standardized biofilms and characterizing biofilm properties as a function of spatial and temporal variations in chemical and mechanical properties; and (ii) application of dielectrophoretic techniques for droplet manipulation in the formation of templated liposomes.

dielectrophoresis

Dielectrophoresis is the motion of particles due to a non-uniform electric field.

electrothermal flow

Electrothermal flow results when electric field-induced Joule heating creates spatial variation in fluid electrical properties resulting in localized bound charge densities that are then subject to significant Coulomb forces.

cell charactarization

Dielectrophoresis techniques, along with detailed cell modeling, can be used to characterize cell composition.

biofilms

Biofilms are interface-associated colonies of bacteria embedded in an extracellular polymeric substance.